The NEFL Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to NEFL, NF68, and NFL. This antibody recognizes Human antigen. The NEFL Antibody has been validated for the following applications: Immunohistochemistry.
Description
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y